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Soft_Rough8721

My wife passed 5 months ago from colorectal cancer. She was 48 when diagnosed. Stage IV. She did not smoke. She was not overweight. She walked several miles a day, preferring that over driving. She ate healthy, mostly fish, and vegetables. Occasional red meat. She loved sweet potatoes and squash anything she could grow. Tomatoes, etc. How in the world she presented one day with pain and blood in her stool, at stage 4, is still a mystery to me and her oncology team at DFCI. DFCI is probably the leading hospital / research organization in the US. When they are stumped, you know there's a problem. All I can say is I don't care if your insurance won't cover colonoscopy screening at 45 yo. Find a way to make it happen, particularly if you are a female. New incidents of CR cancer are increasing over 2% per year, and have been for the last 25 years. That equates to a doubling of cases in that period. I hope we figure it out. I don't want ANYONE to go through the agony I have and will continue to go through. There are no words.


plainbagel11

I’m so sorry your wife passed and you’re going through this. I agree it’s bull shit that insurance companies won’t convert it up to a certain age.


Soft_Rough8721

And thank you for sympathy. It's just brutal. She's going to miss so much and she went through hell fighting.


Spaceredditor9

I’m really sorry for your loss. How is this possible? Good diet, fit, middle aged. Was she under stress/anxiety? That’s the only other thing I could think of although I doubt that alone could cause something like that.


Soft_Rough8721

She did suffer from anxiety. But not the point of incapacitated. In fact people loved being around her. So I don't know


odods11

There's so much we don't know about cancer. Sometimes it's just getting unlucky with a spontaneous cellular mutation and there's absolutely nothing that can be done about it. I hate how people always try to put the blame on cancer patients. It's a way of deflecting from their innate fear of the randomness of the world and their unfounded belief that "it could never happen to me because x reason"


Unlikely_Lily_5488

well, sure. but also, people want to know what they can do to reasonably avoid risk. we didn’t used to know smoking caused cancer. when that information was then spread around, would you have said the same thing? lol. some things actually DO increase or decrease the odds of some types of cancers by a lot. some of it IS within our control to influence.


Soft_Rough8721

My kids now have to get screened when they are 35. I asked if insurance will cover that and answer was probably not. I hate these people. It's still a way off for them (17 and 15) but still. It's just infuriating


nychthemerons

Health insurance companies are evil


jerkularcirc

there’s an inherent conflict of interest with your health when denying more treatment makes a company more money atleast with a healthcare provider the money is aligned with doing more for you how more people don’t see this baffles me


Fromage_Damage

Cologuard is probably not terribly expensive out of pocket. The internet says $600. So it's a lot but not terrible.


DiscoveryZoneHero

I got a covered colonoscopy under 30 because I had bleeding. Have your children say there’s occasional blood and it’ll go through easier. Fuck insurance and FUCKCancer. I really had bleeding fwiw, 1 benign polyp was found too. Now I’m on a 5 year schedule after a clear screen in 2022 so sorry for your loss and wishing you and your kids the best life can offer going forward.


Most-Stay6946

Im so sorry man. Im sorry bro. Youll keep her forever in your heart, Im sorry man. She was so young


Soft_Rough8721

Too young.


PrettyOperculum

I’m so sorry this happened to you. As a woman in her 40’s who had never even considered asking for this, thank you.


Puzzleheaded-Will249

My nephew discovered he had colon cancer when he was 21 and passed away from it at 24. He did not drink alcohol and ate fairly clean. They did not discover it until the tumor was large enough to block his colon. He had intestinal problems and had numerous doctor visits, but the doctors would not authorize a colonoscopy due to his young age. By the time they discovered it, he was terminal.


Illustrious-Study237

This. I’m really tired of medical professional dismissing issues in young people just because they’re “young”


pandaset

This happens so much here in Japan, it's outrageous


fitbeard

Japan's approach to preventative medical care is atrocious by international standards. They have excellent diagnostic tools and very educated doctors, so if it fits on a checklist you're golden. Just don't ever dare to have a condition that requires critical thinking or an investigative approach.


squackbox

I am curious about how other countries feel about their healthcare. Thanks for sharing .


opusxfan

Dude the medical system is so rigged. Most people aren’t going to ask for a colonoscopy unless they know something is wrong internally. Just give it to a guy. U know it was probably actually the insurance company saying that they would not cover the cost because of age.


CaptainTepid

Hormonal problems as well, I’ve been in the ringer with doctors for 2 years over extremely low hormones and they just call me a junkie looking for testosterone when I just want to know why I have the testosterone of a 90 year old


RobbyZombby

I ended up contacting Renew Vitality for TRT. Mine was not “low” but was getting within the ballpark of “low”. A doctor refused to have a discussion with me about my levels even after they were tested as far lower than average and not where they should be. Before I got onto to TRT I was struggling to heal lower body injuries from a small car accident, the TRT helped those injuries heal well and my energy is up.


PersonalitySad3753

They hate giving men testosterone because it literally solves 95% of our problems. There is a solid testosterone deficiency amongst all men. Ive had 3 buddies gets tested and theyre all low, and now on TRT. they feel amazing now


nerissathebest

They hate giving women testosterone too, they hate learning anything about HRT but especially replacing our testosterone so that we can live normal lives again during menopause and perimenopause, no they’d rather eat glass. 


Fosterpig

I finally thought to get my T checked after cycling on and off about 10 antidepressants trying to figure why I always felt like shit, no drive, no libido. . . When I found out it was such an easy test I was kinda pissed nobody said he let’s take a look at this to rule it out.


stever71

TRT is not a magic bullet, it can cause all sorts of problems in many and literally nobody fully understands the complexities of human hormones yet.


khaleesibrasil

Go see a functional doctor they will actually help you. Allopathic doctors are given a window to average 15 minutes per patient and are not properly taught or trained to get to root cause.


CaptainTepid

What is a functional doctor in this situation


khaleesibrasil

functional doctors treat root cause. They unfortunately are harder to be covered by insurance though, but most people are desperate enough to go see them after the system has failed them


thespermof78

Louder!!! 👏👏👏


Spaceredditor9

This is very strange. Especially when you say things like he ate clean! No processed food or anything? How does someone that young, healthy with a good diet get colon cancer!? Scares the shit out of me!


PissBabySpez

By rarity. There are edge cases for all diseases and even those who live the best lifestyle will get horrible diseases the same way someone who abuses their body day in and day out could by luck avoid the reaper for a long long time. Nothing is binary.


Spaceredditor9

Like the chainsmoker who lives well in his 70s and still chainsmokes vs the nonsmoker guy who gets lung cancer at 60 who was completely healthy.


LineAccomplished1115

A friend of a friend died in a similar fashion, just a bit older, like mid/late 30s. Still a pretty healthy guy, good diet and regular exercise. Lesson learned, if I start having weird digestive/intestinal issues, I'll shove a camera up my ass myself if I have to.


emilstyle91

Its random genetics. Cancer is 80% random genetic and 20% what you do. If your genes are prone to errors when they duplicate, then you get cancer much earlier in life


Spaceredditor9

I can’t wait till we get good at genomics to the point we can live edit the shit out of anything for everyone at low cost accessibly


odods11

Diet does not cause colon cancer in your early 20s regardless of what you eat. (At least there is no evidence to suggest this yet). Colon cancer at this age is a result of a random mutation and there is basically nothing you can do to prevent it.


coppersocks

Well if cases of colon cancer in the young are going up by a lot then there is clearly some environmental factor at play that increases the odds of getting it. Theoretically if those variables can be identified then you could potentially reduce your chances of you could effectively avoid them.


OptimistRealist42069

Eating meat has been linked by many studies to increased incidence of Colon cancer. 30% increase for red meat. 40% increase for processed meats. There is also a large study (70,000 people) that was released earlier this year that shows people with a certain gene are at a higher risk of colon cancer from eating meat. Maybe they just had the gene and were unfortunately unlucky. Here’s a link; https://aacrjournals.org/cebp/article-abstract/33/3/400/734666/Genome-Wide-Gene-Environment-Interaction-Analyses


mmxmlee

why do people not understand that cancer is often completely random. has no reason.


harmothoe_

It's too scary to accept. When someone else faces something awful, people reach for reasons it couldn't happen to them. Watch what happens when a nonsmoker gets lung cancer. People are shocked that it isn't "their fault".


longevityoptimise

I’m sorry to hear that. That’s a real issue I hear with young people getting cancer is doctors saying yeh it won’t be cancer your too young.


Top-Watercress2936

Surprised they didn't see something like that something simple like a CT scan? Thats how my diverticulitis was determined.


ellemed

CT scans are not very sensitive for colon cancer until the mass is pretty large. Also insurance does everything they can to block covering a CT or a colonoscopy in a person that young. Don’t blame doctors - blame insurance companies for trying to practice medicine


Moetown84

And the politicians that take their money to continue the scheme.


Sautry91

You can still get a colonoscopy when you are young but it usually billed as diagnostic instead of cancer screening, so it’s still on the doctor to recommend the diagnostics.


Comrade_Do

I’ve wondered this also. Would a CT scan even see it? I got downvoted in another forum just for asking.


FrozenJourney_

I'm so incredibly sorry. This is devastating and sadly not surprising if it happened in the US. Those in power who run the insurance companies and healthcare industry ought to be ashamed of themselves.


Furbjunior

When did he get it? Which year?


Legal_Squash689

Certainly a major cause for concern. As alcohol consumption rates are declining, doubt it is a significant causal factor. Think more likely factors are 1) dramatic increase in consumption of processed foods, 2) exposure to tens of thousands of new chemicals developed in past 50 years and 3) exposure to microplastics in everything we eat and drink.


eloaelle

to add to #2: not only is it new exposure to new chemicals, it's more exposure more often through multiple channels: eating, breathing, touching. Besides blood donation, there's little we've been doing to get rid of these chemicals from our blood stream and organs.


jsilk2451

I know it’s crazy to me to see how many IV clinics are up everywhere. We have known for decades now that iv fluid bags leach microplastics and other chemicals used to make the bags. Then people are electively shooting this straight into their vein without any sort of filter and no medical reason (dehydration/inability to drink etc). All in the name of being proactive in their health.


Special-Garlic1203

I don't understand why plastics are still so integrated in bougie healthcare. I get that it's cost effective, but if I was a rich person I'd want glass syringes and glass bottles like back in the day. I would gladly cover the additional shipping expense and overages for what breaks. I genuinely don't understand why there isn't a whole boutique market for it 


yachtsandthots

I’ve thought about this too. Seems like there’s a market for it


Downtown_Samurai

Any data to support this?


ModsareWeenies

Facebook memes


Slammedtgs

I’d also argue the lack of fiber, which could be a result of increased processed foods but also other reasons too.


22marks

Obesity, lack of exercise, and lack of fiber (while eating high-fat diets) are major contributors, according to leading medical centers, like the Mayo Clinic. We should be getting 22-34 grams of fiber every day, depending on gender and age. I think the average person would be shocked at how little they actually get. By way of example, if you ate a banana (3 grams), an apple (4.5 grams), a cup of strawberries (3 grams), a cup of brussel sprouts (4.5 grams), 2 carrots (3 grams), and a bowl of oatmeal (4 grams) every single day, you'd be scraping by at 22 grams of fiber.


cecsix14

Refined carbs and sugar are bigger contributors to the problem than fat, IMO. The processed foods that are high in fat (pork, cold cuts, etc) are definitely a big part of it, but that is more about the curing and processing than the fat itself. Many natural fats are quite beneficial and should not be avoided. There’s almost no benefit to sugary sweets or simple carbs. Whole grains and other Whole Foods that are high in fiber are great, but unfortunately too many people are still opting for the refined stuff.


[deleted]

[удалено]


Slammedtgs

The bar is far too low. My 8 year old child always wants McDonald’s and packaged snacks (can’t blame them, they taste good). But damn is it hard to get them to eat good food. I’m no role model but I try my best to eat quality food. I eat a lot of fat (cheese and meat) but generally minimally processed and only ingredients I can pronounce.


SitaBird

That’s sort of eye opening. There is no way I eat that much fiber everyday and I consider myself a healthy and somewhat fit pescatarian….


22marks

Yeah, what opened my eyes was buying a "high-end" fiber supplement with chia seeds, flax, and various sprouted legumes. Not just the typical psyllium husk. I add it to a shake I have for breakfast every morning\* The total fiber it added was *10 grams* for a decent-sized scoop. That's what got me looking into how difficult it is to regularly hit 30 grams of fiber. \*My shake is a scoop of whey protein, banana, cashew, and mint. Then, two chlorella and spirulina tablets, a dropper of 3000IU Vitamin D with K3, 500mg cocoa flavanols, and a scoop of Kachava. I alternate between water, oat, or soy milk.


life3_01

Fat is not the issue. We have more sugar than ever in our diets. Fat has been ostracized and it’s being blamed for the damage that sugar does. We stopped eating commercially processed food of any kind 8 years ago and now at 59 and 60, we have the best health of our lives. Of course my doctor say I eat too much fat and red meat but can’t argue with results. 0% of our food comes from a grocery store. I don’t trust anything in them. The difficult part is traveling anywhere in the US. Restaurants are using cheap GMO crap and feeding you with it. I asked one if I could see their butter label. And they bring out margarine. We left.


Hungry_Line2303

I agree with all of this except refusing to buy food from a grocery store. That's absurd.


22marks

Note I didn't say fat was the issue, but eating a high-fat diet without enough fiber.


WizardLizard1885

microplastics are a huge factor.. scientists in the 80s growing human tissue samples had irregular growths because the plastic petri dish was causing hormones and other strange things to alter the samples. microplastics are going to kill everything on this planet eventually


AncientGrapefruit619

I agree with this. Microplastics are everywhere, including men’s penises. Apparently they found 4/5 of men tested who had ED had microplastics in their peen.


nessarocks28

The sheer amount of people I see drinking out of packaged bottle water is astounding. And someone who worked in a factory once commented the plastic is so flimsy that it 100% is leaking tons of micro plastic particles into water. I drink out of glass as much as possible. Just came back from a resort in Cancun. They can’t drink tap water because of the mineral content. They had bottled water shipped in by the thousands… one resort. 😳 I myself probably drank 50 bottles while I was there. (They where small and it was go awful hot)


pomnabo

The vast proliferation of gums as emulsifiers is also a problem. They’re in just about every processed food out there these days! Heck, they’re even in cosmetics too! In moderation, they should pass just fine, but when every food and beverage has some amount of carrageenan, xanthan gum, guar gum, acacia gum, locust bean gum (the list goes on), then it can form a film in your small intestine and prevent adequate nutrition absorption and choke the scillia. Additionally, carrageenan has been found to irritate the skin. This can lead to a whole slew of other health issues like SIBO, IBS, etc., and I wouldn’t be at all surprised if these gums are eventually linked to cancer in some way.


Chaotic_Good12

I'm avoiding packaged salad dressing (like Ranch) because of the Carrageenan and its inflammation causing effects. Thats ok, was an easy and delicious switch to olive oil and aged basalmic! Then I just found out the other day here on Reddit (thank you Reddit peoples!) that all Crest toothpaste has it as well. FML! 🤬 what evil is lurking in my mouthwash!? Kryptonite?!


brimonge

This! And what truly amazes me is that everyone points to other things even the so called scientists. The amount of new chemicals we are putting in to our system is more than in any other time. It doesn’t take a genius to correlate the two. Other effects autism, transgenderism, obesity and many other diseases


NoWorldliness6660

>This! And what truly amazes me is that everyone points to other things even the so called scientists. It's because there is a lot of money in selling shitty, addictive food and those companies are usually the ones funding "research".


tiggahiccups

It reminds me of the holiday themed aisles at the big stores that have aisles and aisles of plastic themed crap we don’t need to waste our money on but most people do. It’s like that with our food now. All these new themed items, special flavors, crazy combinations….. and all so full of dye and sugar. There is so much sugar in our food now.


the-blazing-world

I don’t really go to big stores, but every time I walk into a (U.S.) “pharmacy,” like CVS or Walgreens, I feel like I’ve entered another dimension lol. Aisles of candy and crap and “special holiday items” of candy and crap everywhere. Like, no Mr. Walgreens, I do not want your 4th of July-themed high-fructose corn syrup red/white/blue gummy clusterfucks.


longevityoptimise

THANKYOU, I feel like I’m going insane arguing with this person who’s saying nah that’s not true it’s because people are eating more due to thermodynamics it’s nothing to do with processed foods and the garbage they are eating.


NoWorldliness6660

The issue with processed foods is that they are literally designed that way. They design their food to be highly addictive so you to overeat and buy more of their stuff. They also love putting cheap ass "ingredients" in their food just to maximize their earings and claim it is a "new & better formula". It is really an interesting field to look into, and extremly scary once you realise how fucking hard you get manipulated by the food industry.


Canuck_Noob75

Yes! Food Scientists make a ton of money to create “food” that is addictive. Putting ppl in hospitals so only they and Big Pharma profit. Small children getting adult onset diabetes and early stage heart disease, cmon ppl we have to take our health into our own hands and pass this info to the next gens or we will perish as a species!


NoWorldliness6660

They are not only trying to make your food addictive - their goal is to create a product that is highly addictive and as cheap as possible to produce. You get the lowest quality possible. >cmon ppl we have to take our health into our own hands and pass this info to the next gens or we will perish as a species! That isn't the issue. The issue are governments who don't care. Certain additives are known to be a risk to your health - still basically no one cares enough to forbid them. Many of them are not well researched at all and we still allow this stuff in our food. We need a government that cares about its people, and not just about companies that would let you die if that means they earn one penny more. Lobbying needs to get punished with a very high prison sentence for politicians and hefty fines so politicians can start to focus on the population of a country, and not just the top 0.1%


poop_on_balls

Don’t argue with idiots. They will drag you down to their level and beat you with experience lol.


only_star_stuff

(1) in teenagers and young adults, disruption of gut micro biome by long-term intake of systemic antibiotics (such as doxycycline, minocycline) for treatment of acne


MasterpieceLost4496

Oh this is an interesting one!


theriz123

Colonoscopies are done at 45 years old. I’m much younger than that but bought something called a second generation fit test. When i tested my stool twice, the results were positive both times, meaning there was blood showing up where it shouldn’t. I got a colonoscopy and they removed several polyps. I would definitely recommend testing yourself, if you haven’t yet. It could save your life.


LifeisFunnay

How has your life changed after removing the polyps? Was the surgery and healing process difficult in any way?


theriz123

The colonoscopy was no big deal, they knock you out for it. When you wake up, you don’t even know it happened. Leading up to the procedure, you have to cleanse your colon so you shit none stop for a few days, that’s the brutal part. I haven’t seen any difference in my life other than no longer seeing anything red in my poop. The lab results came back negative for the polys being cancerous but the doctor wants me to do it all over again next year since i had 3 this time and one was over 20 millimeter which is quite large


No_Needleworker_5546

Was it very expensive?


theriz123

$15-$30 on amazon. It looks like they’re no longer selling the one that i used a few months ago.


No_Needleworker_5546

Wow not bad at all!


dr_progress

Processed food, including sugar, conservators (nitrites, etc), poor quality and chemically processed vegetable oils, etc etc And of course pesticides.. Not sure about microplastics, curious to learn more.


jakl8811

I think it’s still pretty unclear what the cause is, but one of the factors is obesity and physical inactivity - which we’ve definitely seen increased in the last 50 years.


Efficient_Smilodon

living the early decades of one's life essentially in a sedentary mode while binge eating is the symptom of major cultural illness that most suffer from as a consequence of the perversion of purpose rendered by modern capitalist economies.


longevityoptimise

My theory was its the diet filled with supermarket processed shit that makes people eat even more even when they are full leading to obesity and filling there bodies with nasty shit


poop_on_balls

I concur with your theory. The toxic garbage being called food is the reason over 80% of America is metabolically unhealthy. I’m not really sure why there’s even any question about what’s making everyone sick, obese, increased cancer rates, mental health issues etc. Some of the shit that is put in our food is so well established to be inflammatory that it’s used in vivo to elicit inflammatory responses. And you find this bullshit in everything, it doesn’t really make sense. I mean why tf do you need to put carrageenan in a coffee drink? Or all the bs that used polyethylene glycol as a sweetener. Polyethylene glycol is also used to test the permeability of our guts. So I’m sure the other bad shit I’m the toxic food is bonded to the PEG and causing inflammation after it permeates.


UnlikelyDecision9820

In response to the inflammatory additives, can you name a few of these compounds or link to a study where they’re used to illicit inflammation? I’m assuming you mean in vitro instead of in vivo, but interested to be proven wrong


AndreaSys

Agreed. Obesity is a huge factor in this. Now what causes that obesity is open for discussion, but that’s the issue.


Learningstuff247

Aren't young people actually drinking less alcohol than previous generations? I mean, I'm not, but I think the majority are.


MasterpieceLost4496

Yes. Each year that goes by it seems like the people who go sober doubles. It used to be unheard of for me to meet people sober from alcohol entirely, now, it’s becoming a norm. I am one of them.


SlackerNinja717

In my opinion - more processed foods and not enough fiber.


MoonMouse5

My brother died from colon cancer at age 39 a couple of years ago. He was a drinker but nothing extreme, and at the time and for a few years prior he had been a vegan. Not sure what the cause was, all I can say is that it sucks.


longevityoptimise

I’m so sorry to hear that, that’s very unfortunate I hope more study’s and information come out


mynof1

My hunch is it caused by the “standard American diet” with all the chemicals, GMO ingredients and traces of herbicides and pesticides that come along with eating all the processed products. There will never be one food or ingredient that is the cause but rather the steady state of inflammation that is caused by constantly eating combinations of inflammatory agents in all the processed foods. Every person will have different things that inflames them so no study will be able to identify a single cause.


longevityoptimise

That would have been my guess also


momdowntown

Younger people are increasingly suffering from obesity, type 2 diabetes and a lack of exercise. Those are the all carcinogenic


thorne-discount

I think it has much more to do with processed foods, the sprays they use in conventional farming and the packages our food is processed in than the consumption of red meat.


justtrashtalk

RED 40, its been in Skittles, Twizzlers, Hot Cheetos since we were kids. Check anything with a bright color that came in  a package and prolly has red 40. even if its not directly affecting us by now, it could be disrupting shit in our guts since we were kids, its cancer causing. if you can't think that might be it, then you prolly also waiting for the government to confirm aliens. they know this shit is bad. they used to put LEAD in gasoline KNOWINGLY. people need to wake the fuck up, its what we are eating....


4list4r

Didn’t skittles get sued for titanium dioxide?


longevityoptimise

crazy how they get away with so much of shit like that


justtrashtalk

that's just what we know and they have out in the fucking open like that. imagine what we don't know we fund with our tax dollars...


longevityoptimise

It will all come out soon hopefully!


Unwieldy_GuineaPig

It’s also in quite a few prescription and OTC medications.


fitfinatic

I didn’t pay Red 40 any mind until I recently read a study on it and my god. It’s outrageous.


paper_cutx

I read an article about this and a colon cancers doctor interviewed stated it’s the lack or low intake of fiber. We’re eating more processed foods and all processed foods are low in fiber


JESUS_PaidInFull

The crap food that is made so easily available is killing us.


Intelligent-North957

Poor diets ,sedentary lifestyle,genetics only play a small role. I had a couple family members pass away from it ,they had something in common,poor diet and alcohol consumption.One in particular was a BBQ lover who liked that char .


junglehypothesis

I’d say it’s multiple causes combined: * People never used to eat all the time, but dieticians around the 80’s decided people should snack all the time and never be hungry (i.e. fast, which has many proven health benefits). This never gives the digestive system a break and causes blood glucose and insulin to be elevated, leading to insulin resistance. Many people don’t realize that cancer cells are “evolving”, they strive to become immortal and instead of using mitochondrial ATP for energy, learn to ferment glucose. * Foods became much less fibre rich and ultra processed. Some would say the reduction in fibre intake has been catastrophic for gut health, and we now know so much is dependent on good gut health, including mental health. Nobody in the 80s or 90s ate a bag of Flaming Hot Cheetos for lunch. * New intentional additives in foods since the 80s for cost reasons, including new hybridized dwarf wheat which is high in amylopectin (spikes blood sugar and causes systemic inflammation), high fructose corn syrup, and seed (“vegetable”) oils. Some might dismiss seed oils (like canola, soy, corn, etc), but they are unstable and readily oxidized, if not already rancid when you eat them. Being high in Omega 6, they are also pro inflammatory. These oils were rarely consumed by humans until very recently and now make up over 10% of the daily caloric intake of Americans. If a person overconsumes unstable seed oils, their cells including lipid membranes are increasingly made from them. * More unintentional food additives like microplastics, PFAS, glyphosphates (probably more intentional!), industrial contaminants, etc. * All of the above have affected the gut’s micro biome in a negative way. The micro biome is pivotal to health, and gut disfunction now appears to be the root cause of many seemingly non-related diseases like MS. * Iron fortification in foods. This is bad for many reasons because iron is so reactive and it also alters the guts micro biome. It’s also a fact the duodenal cells of the colon store iron and we know so little about the mechanism of iron absorption, we don’t fully understand how iron converts between FE2 & FE3 as it makes its way into the blood. Also, bad bacteria thrive in iron rich environments and cause inflammation. In fact your body knows this and pulls iron from your blood (storing it away) when it detects an infection, because bacteria love it so much. In the west, there’s little risk of anaemia, however all cereal in the USA is mandated to be iron fortified and virtually everyone eats cereal. However the Danish have banned this practice of iron fortification and many should follow. Excess iron could very well be a major factor. * Less quality sleep due to increased screen time and more LED blue light. Kids especially used to go to bed earlier without as many distractions and be outside more of the day in the daylight. Internal lighting was also incandescent with more infrared and less blue light. The lower melatonin due to this shift in light exposure and sleep is poorly understood, but we know melatonin is the body’s most important anti-oxidant. * Less physical activity. * More stressful lives with economic Ponzi scheme pressures (the fiat system) now placing undue stress on younger generations who will likely never own a home. Their parents (if both around) are now both usually working full time due to economic design, leading to less time to prepare proper food, so relying more on fast food. Overtime stress and poor diet has a pronounced negative effect on health and is why, in addition to the above reasons, many Gen Z’s already look older than generations Y and X. * Potentially, being surrounded by more EMF radiation all the time. More powerful devices (transmitters like iPhones, which if you read the terms say you shouldn’t place near your body) and WiFi literally everywhere.


stephg78240

Finally, a good response.


Not-a-Cat_69

its not the red meat or the alcohol, its the fucking twinkies, flamin hot lime dusted cheetos, coca cola syrup that makes the drink 75% sugar, mega ultra stuffed oreos, proliferation of fast food, etc.. all the junk / processed food


PrepareToBeLetDown

I never really drank alcohol before my stage 4 diagnosis at 23. So yeah, I call bullshit :) I have no known genes that would make me more likely to get colon cancer. It's a generally unhealthy diet/lifestyle, stress, pollution/micro-plastics in my experienced opinion. Also grilling anything basically makes it carcinogenic 🙃


picklesalazar

How does grilling make something carcinogenic?


Jealous-Key-7465

Glycation, or the formation of advanced glycation end products (AGEs), can occur when foods containing sugars and amino acids are exposed to high temperatures, such as during grilling. This process is called the Maillard reaction, and it can produce up to 100 times more AGEs than other cooking methods. AGEs are harmful compounds that can also form when protein or fat combine with sugar in the bloodstream. P


longevityoptimise

Sorry to hear that, how are you doing now ?


PrepareToBeLetDown

In September I'll be 3 years remission/NED (no evidence of disease, preferred term over remission). You can see my full cancer timeline here. It was written to be shared with new doctors and other cancer patients. So many terms are probably foreign to those not listed above. Feel free to ask me any questions. https://www.reddit.com/r/coloncancer/comments/1cwyxgb/29_confirmed_months_ned_31_months_including_time/


longevityoptimise

That’s good to hear your all clear!


ncdad1

I am betting on a lack of fiber from a diet based on fast and processed food.


Andorrano90

Fast food restaurants are full of people every day eating shit


Footprints123

Funnily enough I am currently having investigations for colon cancer at 35. I live a pretty healthy lifestyle. Don't smoke, drink a glass of red wine on average once every two weeks, exercise, eat home cooked, balanced food etc. I asked the consultant about this and he said he sees it in young people who eat a healthy diet just as much as young people who don't . In those who are otherwise leading a healthy lifestyle it is his view that it's a mixture of genetics (those who have colon polyps) passing it down so more people are born with the risk (which is certainly the case for me) and exposure to environmental pollution such as microplastics, air pollution etc.


beland-photomedia

Microplastics + dental bacteria = the problem. Recently discovered that the bacterial overgrowth in your mouth will cause colon cancer. Better get to the dentist. Source: https://www.nih.gov/news-events/nih-research-matters/gum-disease-related-bacteria-tied-colorectal-cancer


semisolidwhale

Source?


VelociraptorRedditor

https://www.nih.gov/news-events/nih-research-matters/gum-disease-related-bacteria-tied-colorectal-cancer#:~:text=A%20bacteria%20implicated%20in%20gum,outcomes%20than%20tumors%20without%20them. "A bacteria implicated in gum disease, Fusobacterium nucleatum, has also been found in some colorectal cancer tumors. F. nucleatum is rarely seen in the guts of healthy people. Colorectal tumors harboring these bacteria are associated with more cancer recurrence and worse patient outcomes than tumors without them. However, it’s unclear how much of a role, if any, the bacteria play in causing the tumors to grow."


CoffeeChesirecat

Also interested in a source My dad was just diagnosed with Stage IV Colon Cancer. He is in his 60s, but I'm young and for the first time in my life, devoting brain cells to cancer prevention. The rising incidents of colon cancer in younger people are concerning.


semisolidwhale

Sorry about your dad. I wish we had more answers to this instead of just speculation. I'm 42 and going through chemo right now for stage 3 colon cancer. Wasn't obese, didn't drink, didn't eat as much meat as the average person, no family history, etc. Would be nice to have a better understanding of the true cause of the uptick so that people can do more to try to avoid this, because it sucks. In the meantime, hopefully some good comes from your dad's diagnosis in terms of making sure you get your screenings etc.


CoffeeChesirecat

I'm so sorry. I hope you kick cancer for good. You are still young and have a lot of fight left in you. My dad has been obese most of his life and loved processed meats, so we understand that's probably how he got here. It doesn't make it any easier to deal with, but it's certainly changing the way I look at my own health.


421Gardenwitch

It’s hard to get away from processed foods for some, and sugar especially high fructose corn syrup is added to so much. *The findings were striking, Yun says. Consuming the equivalent of just one can of soda sweetened with high-fructose corn syrup per day led to the development of more and larger tumors, even though it didn’t affect weight*. https://www.mdanderson.org/cancerwise/do-sugary-drinks-increase-colorectal-cancer-risk.h00-159698334.html


unswunghero

More and more processed foods as a staple of people's diets and not enough fiber/vegetables to push food through the GI tract. It's basically that simple. The incidence of colon cancer is directly attributable by fiber/vegetable consumption, and this was used to create the false claim made by vegan advocates that being vegan had a lower incidence of cancer than omnivore diet. But when they factored in fiber/vegetable consumption, both meat and vegans had a similar incidence of colon cancer. However, consumption of processed meats will create a higher incidence of cancer.


-GuardPasser-

So many people just don't eat vegetables. I'm not sure alcohol would have much effect


AncientGrapefruit619

Widespread use of glyphosate would be my guess


OkCaptain1684

Stress, lack of sleep, diet, lack of exercise. I think stress is the biggest factor, we all have tumours in us but most do not grow cancerous as the immune system is strong enough to keep them at bay, when we have too much stress it depresses the immune system and the tumours get out of control.


sunqueen73

We do know the body grows cancerous cells all the time. For whatever reasons, whether by exposure to something external or a genetic lack of something, certain cancers are not seen by a persons immune system. So the problem is that the immune system isn't catching it. covid has pretty much destroyed many people's immunity, and we will see an even higher rise even still of all cancers over the next ten to twenty imho.


matrixunplugged1

Could be so many things, plastics have shown to have negative effects on the hormones, chemicals everywhere especially in processed food, sedentary lifestyles.


Plain_Chacalaca

Plastic lined coffee cups, food cooked in hot plastic, plastic lids leeching chemicals into your drink - basically, plastics and other chemicals in food, drinking water and other products. Fatty food, air pollution, sedentariness. 


DesertFarmer_

People aren’t eating enough fiber and are eating too much junk


Studio-Empress12

I think sitting. We sit at work, come home and sit at a PC or game console.


Little-Principle-150

Eat lots of wild-caught fish, fiber, and a ton of vegetables. No fast food and limit processed foods.


britlover23

environmental and agricultural poisons


SapienWoman

It has to be our food system. And microplastics, probably.


Impressive-Cold6855

What can we do about microplastics? The damage is already done


heartvalse

Potentially unpopular or controversial possibility: * Vitamin and supplement consumption rates have skyrocketed in the last 20 years. Depending on the source you reference, consumption has nearly doubled over that time. For younger adults, the increase has been even greater than all 18+ consumption rates. * There is virtually no oversight or regulation of the industry. * Commonly used additives, fillers, binders, and flow agents can be highly contaminated with toxic substances. * Vast amounts of the vitamins and supplements people are consuming are ultimately sourced from countries with very poor safety records and regulatory environments. I could continue the list but the gist of it is that vitamins and supplements need greater scrutiny. I'm not proposing that they are the sole cause of the rise, which may be multi-factorial, but it's shockingly myopic to me that Americans completely turn a blind eye to this. There was even a document by strategists of a major American adversary that suggested intentionally contaminating consumable exports with carcinogens could be a viable form of asymmetric warfare to weaken a geopolitical super-power like the United States. The FDA is currently a staggeringly inept bureaucracy that probably could not in its current state take on the task of greater regulation and scrutiny of the vitamin/supplement industry but it is long overdue.


austinwiltshire

Red meat consumption peaked in the 1970s. Alcohol has been on a decline for years. Your "scientist" needs to actually look at the data.


longevityoptimise

Thankyou, can’t believe this person has over 90k followers and is saying mental stuff like that and that organic beef and fruit/veg has no difference whatsoever and also that most energy drinks are zero sugar then I listed a handful of energy drinks that are full sugar for the person to say Diet Coke is fine. If this person didn’t have 90k I would have thought they were trolling by now


austinwiltshire

That's weird because artificial sweeteners certainly have come under scrutiny for disrupting the micro biome.


Flipper717

Sugar is in everything and it’s been steadily increasing in things at grocery stores except the perimeters of fresh produce, etc. Meat consumption that is full of antibiotics. Chemical exposure in daily life that accumulates in the body.


Affectionate-Duck-18

Processed food in place of fresh vegetables and fruit = much less fiber. Look around you. Fast food and processed packaged meals are the norm.


evetrapeze

Less and less people are cooking from scratch. Could processed foods be contributing to this problem?


Blacksunshinexo

It's all the chemicals, PFAS, plastics, etc they're pumping into our food, water, products


Additional-Silver505

Still. Fast food and no exercise.


SpeedingTourist

I don't think anyone really knows for certain at this point. But lack of activity and poor diets almost certainly contribute.


streetsoldat

I think it is all of the chemicals and GMO foods that we eat. The food industry wants to blame it on something else. Also the toilets are too high, squatty potty for the win!


Vegetable_Assist_736

My theory is that it’s not the red meat itself that’s causing the health issues but what the animals are being fed and what companies are putting into our meat.


checkyourearsbro

On top of the already discussed poor diets, most calorically dense foods have poor fiber content. Fiber can bind to potential carcinogens, preventing damage to the colon lining. Eat your veggies kids.


coastguy111

Recently read that leaky gut is causing the increase on colon/rectal/anal cancers. I like going on the internet archive to find books etc that are readily not available anywhere else.. anyways, I came across the physicians handbook of 1700s. It's amazing how far we have gone backwards regarding our allopathic health care system we have currently..a common theme throughout the books cures is the importance of evacuation of the bowls to stay healthy.. sounds like gut health was extremely important centuries ago.


arguix

I’m going say not the red meat, as you said, consumed 1000s of years, and instead is the massive amount of carbs and sugars we eat


longevityoptimise

That’s most likely


DeadCheckR1775

Plastics, sucrose, industrial oils/additives/preservatives, GMO’s.


DruidWonder

Processed food consumption, chemical exposure in almost every facet of life, lack of exercise, reduced access to medical care, and care that is substandard when you do it get. I don't think red meat is a huge factor since prior generations ate more of it than we do. It's industrial red meat that's the issue.


DipoleExperiment

I'm wondering if HPV is playing a role. Time will tell, since there is now a vaccine for the strains that are most likely to cause cancer.


madtitan27

Yes meat and alcohol have been consumed for thousands of years.. but the amount has increased by astonishing amounts. People on average now eat more than ten times more meat than they did even 100 years ago.. and that meat is raised in far worse factory farm conditions. Add to that super processing of said meat (and other foods) and you got a really bad situation. The generation getting cancer young was raised on fast food burgers, hot dogs, chicken nuggets, lunch meat, pepperoni, ect.. ..it's just world's away from how your great grandparents ate meat growing up.


Beginning_Raisin_258

Obviously something we are exposed to is increasing colon cancer rates in young people. I don't think we can blame poor diet and lack of exercise in general because I don't know if there's any correlation between weight and colon cancer. Whenever I see a sad story about 25-year-old dying of colon cancer they're usually a normal weight. It has to be some sort of chemical or microplastics or something. Taurine found in the energy drinks sounds like an interesting candidate considering energy drinks or a new thing that millennials have been drinking since they were kids.


PeachCobblerVSAppleP

Sugar feeds the cancer; we have the highest sugar consumption in the entire human history, and you wonder why the colon (or whatever) cancer is on the rise? It's not the red meat, it's the good old sugar and high fructose corn syrup that are practically in everything


TheVirusI

Plastic in our balls.


ChakaCake

Processed foods and alcohol for sure play a factor. Red meat has been shown to too but I think thats been pretty constant consumption across time. I think its the new chemicals in processed foods but also could be due to new types of bacteria or virus going around. Intestines are such a complicated area to study


WestminsterSpinster7

People eating like crap and spending too much time on the internet getting stressed out. Like me. I probably have it.


Canuck_Noob75

Technological advancement = sedentary lifestyle


Cautious-Advantage34

PFAS from eating in Teflon pans from birth for decades?


WatchIngYouTime

Alcohol consumption, processed foods, many different preservatives


its_all_good20

Microplastics. Preservatives. Round up


charlestontime

Children's sedentary lifestyle.


RedRosValkyrie

I think it's because we eat less fiber than ever before and have more environmental toxins and prescriptions than in the past.


Content-Airline716

McDonald’s and Fast Food


alarin88

Less physical activity, bad food choices, obesity


lostpassword100000

I think plastics in our guts play a huge part in our rising cancers. I have no evidence to back this up, it’s just a hunch.


EggieRowe

We are nearly at WWII levels of red meat consumption (low) and drink less alcohol than ever - especially younger people. They’re never, ever going to blame processed food consumption which has grown exponential and is a huge profit center.


KarmaKitten17

A family member in his 40’s was told by his doctor that he has the colon of a 70 year old. His entire life…he has been as stubborn as a toddler about avoiding vegetables. I suspect that the culture of eating fast food and processed food has compromised the digestive system of many younger people. Our bodies need the fiber of vegetables to operate properly.


Morticond

At 50 I had my first colonoscopy. They found multiple pre-cancerous polyps. Dr said I was at high risk of colon cancer and it would have been my likely end were these not detected. This put me on the high-risk schedule for more frequent colonoscopies. Dr recommended I eat ‘copious amounts of colorful fruits and vegetables and limit meat consumption to 4oz a week, and further there was no safe level of processed meat. Over the following months I gradually went to a whole food plant based diet. Ten years and several colonoscopies since, I haven’t had a single detected polyp. As a bonus, my total cholesterol and LDL numbers are 140 and 80 with just a micro dose of a statin. I’m now back on the standard low-risk checkup schedule.


longevityoptimise

Glad to hear your doing well and that’s some good advice


tarmachenry

Colorful fruits and vegetables isn't going to help if that produce is heavily sprayed with hazardous pesticides. Can't rinse it off. It goes into the structure of the food.


0nesidezer0

I think it’s due to high consumption of preserved and smoked meats.


kaleosaurusrex

It’s probably all the fucking plastic and other weird ass chemicals getting into our bodies


Harpua2167

Last study I read indicated only 4% of cancers are directly related to alcohol, and the vast majority of those are esophageal and oral cancers. No idea where I read this but could probably dig it up if someone wants a source. Regardless, it’s very alarming that so many young people are getting colon cancer. Hard to understand TBH. A guy I know just got diagnosed with stage 4 colon cancer in his early 40s. The best doctor I know often says that humans go through life with waves of arrows flying past them 24/7. Some people go through life never being it by an arrow while some people unfortunately take multiple direct hits. It’s sometimes hard to predict. Be happy for the health you have and never forget that it can all change tomorrow.


Bigmikey8119

It’s the micoplastics in everything and everyone. 


Addictd2Justice

The answer to this and so many other questions: Eat more leafy green veges.


Slow-Juggernaut-4134

Fried foods. Oxidized seed oil. Modified oils.


p33333t3r

Peter Attia broke down how red meat isn’t actually a carcinogen. He claimed the real problem was a lack of fibrous vegetables + fruits in the diet


Lostsalesman

There are probably several reasons. One of them is due to better detection methods which can increase the identification of occurrences. What’s sounds better, pooping in a box and mailing it to EXAS or getting a colonoscopy?


Different-Instance-6

It's because the US FDA allows way more preservatives and food dyes that are known carcinogens in our food compared to the EU. There's long lists of chemicals allowed here but banned there because of their known potential cause of cancer. Even if you "eat healthy" it's almost impossible to avoid. Not just in food either. At walmart a few weeks ago I was looking for a beach umbrella and there was a huge warning about there's some evidence the plastic used may cause cancer and per a california law they have to disclose it. I mean... Why would there be any incentive to improve the quality of our food when people get paid off of us getting sick? For profit healthcare is undoubtedly a culprit here. Countries like Canada and the EU where the government has to pay for subsidized healthcare means they put higher taxes on things known to cause harm like alcohol and cigarettes and ban harmful chemicals. Here, it's almost like we're incentivized not to improve it and just let it get worse because US food conglomerates and big pharma reps are probably donating huge sums of money to the political campaigns of politicians that will keep things exactly how they are. There's no "bio hacking" to fix this. Only option is to get out of this country in my opinion.


fitfinatic

It’s almost criminal these restrictions on colonoscopies. Also should be criminal to allow manufacturers to continue to use dyes, pesticides, and slew of chemicals with food productions. The FDA is a joke and there needs to be higher accountability throughout. Sadly, it seems more Americans would prefer their individual freedom of choice to choose to consume such products, rather than see companies remove from shelves or change ingredients (otherwise it may not taste the same 🙄).


dyingbreed6009

Covid shot