I'm 28, dx with DOR in September last year. We have been trying since I got the dx but have been unsuccessful. My AMH is 0.03-0.07, AFC is 3, FSH 5.6-10.7. Am I early in perimenopause? I feel like I hear a lot about other people having a lot higher FSH levels.
We're probably going to try IVF starting in the summer or next January depending on insurance logistics. Has anyone successfully gotten pregnant with similar numbers to mine without IVF? Should I try to start some medicated cycles? What about HRT?
The fertility doc is probably going to have more insight, but I know for me, I had much higher fsh (28), so the drugs to make you ovulate more eggs wouldn’t work for me because my body was basically already trying to do that (as evidenced by the higher fsh)…so maybe medicated cycles would be an option for you. I ended up getting spontaneously pregnant after a year of trying with no interventions (.05 amh; never had afc tested).
I’m so sorry you’re going through this. I don’t have the answers to most of your questions, but I did IVF with an AMH of 1.1 two years before starting any HRT and it was successful. I was 32 at the time.
My consultant said to me that that the current studies on IVF success rates in relation to low AMH are not a great indicator of success for someone with POI, because they’re all based on women who are closer to a natural menopausal age. Therefore not only do they have less eggs to use, but the quality of those eggs have naturally declined with age.
There are obviously a million factors that effect this, because most of us won’t know exactly why we’ve got POI in the first place, but in general it’s quite possible that although you have fewer eggs, the ones you do have will be on par in quality with any other 28 year old woman.
I don’t know how much you already know about IVF, but a 28 year old woman has much higher odds of success than someone in their late 30’s due to the egg quality. So if you can manage to harvest enough eggs (that’s the biggest hurdle with a low AMH) then you do have a chance of success.
The odds are still quite a lot lower than your average IVF patient (due to the possibility you won’t get any viable eggs) so some clinics will advise against trying sadly. For me it was worth pursuing and I feel very lucky to have had success. I wish you all the best whatever you decide to do 😊
I'm 28, dx with DOR in September last year. We have been trying since I got the dx but have been unsuccessful. My AMH is 0.03-0.07, AFC is 3, FSH 5.6-10.7. Am I early in perimenopause? I feel like I hear a lot about other people having a lot higher FSH levels. We're probably going to try IVF starting in the summer or next January depending on insurance logistics. Has anyone successfully gotten pregnant with similar numbers to mine without IVF? Should I try to start some medicated cycles? What about HRT?
The fertility doc is probably going to have more insight, but I know for me, I had much higher fsh (28), so the drugs to make you ovulate more eggs wouldn’t work for me because my body was basically already trying to do that (as evidenced by the higher fsh)…so maybe medicated cycles would be an option for you. I ended up getting spontaneously pregnant after a year of trying with no interventions (.05 amh; never had afc tested).
I’m so sorry you’re going through this. I don’t have the answers to most of your questions, but I did IVF with an AMH of 1.1 two years before starting any HRT and it was successful. I was 32 at the time. My consultant said to me that that the current studies on IVF success rates in relation to low AMH are not a great indicator of success for someone with POI, because they’re all based on women who are closer to a natural menopausal age. Therefore not only do they have less eggs to use, but the quality of those eggs have naturally declined with age. There are obviously a million factors that effect this, because most of us won’t know exactly why we’ve got POI in the first place, but in general it’s quite possible that although you have fewer eggs, the ones you do have will be on par in quality with any other 28 year old woman. I don’t know how much you already know about IVF, but a 28 year old woman has much higher odds of success than someone in their late 30’s due to the egg quality. So if you can manage to harvest enough eggs (that’s the biggest hurdle with a low AMH) then you do have a chance of success. The odds are still quite a lot lower than your average IVF patient (due to the possibility you won’t get any viable eggs) so some clinics will advise against trying sadly. For me it was worth pursuing and I feel very lucky to have had success. I wish you all the best whatever you decide to do 😊
Thank you so much for your reply. I'm so glad to hear you had success!